Antihistaminic Pharmaceutical Raw Materials Azelastine Hydrochloride
|5-99 100-499 500+|
|FOB Unit Price:||US $1 US $0.8 US $0.5|
|Purchase Qty. (gram)||FOB Unit Price|
|Transport Package:||Disguised Packing|
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- Model NO.: CAS 79307-93-0
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- CAS No.: 79307-93-0
- Appearance: White Crystalline Powder
- Trademark: Yuancheng
- Origin: China
- Powder: No
- Certification: GMP, HSE, ISO 9001, USP, BP
- State: Solid
- Product Name: Azelastine Hydrochloride
- Fw: C22h25cl2n3o
- Usage: Antihistaminic
- Specification: Pharmaceutical Grade
- HS Code: 2937390000
|Place of Origin||China||Product Name||Azelastine hydrochloride|
|Molecular Formula||C22H25Cl2N3O||CAS No||79307-93-0|
|Payment & Shipping Terms|
|Minimum Order Quantity||10gram||Payment Terms||Western union,Money gram,t/t|
|Standard||Enterprise Standard||Appearance||White Crystalline Powder|
Product Name: Azelastine hydrochloride
Melting point 225--229ºC
Storage temp. -20°C Freezer
Stability: Incompatible with strong oxidizing agents.
Chemical Properties White Crystalline Powder
Usage Orally active H1-hystamine receptor antagonist. Antihistaminic .
Azelastine hydrochloride Application
Azelastine hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis.
Azelastine hydrochloride Description
Astelin (azelastine hydrochloride) Nasal Spray, 137 micrograms (mcg), is an antihistamine formulated as a metered-spray solution for intranasal administration. Azelastine hydrochloride occurs as a white, almost odorless, crystalline powder with a bitter taste. It has a molecular weight of 418.37. It is sparingly soluble in water, methanol, and propylene glycol and slightly soluble in ethanol, octanol, and glycerine. It has a melting point of about 225°C and the pH of a saturated solution is between 5.0 and 5.4. Its chemical name is (±)-1-(2H)-phthalazinone,4-[(4chlorophenyl) methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-, monohydrochloride.
Astelin Nasal Spray contains 0.1% azelastine hydrochloride in an aqueous solution at pH 6.8 ± 0.3. It also contains benzalkonium chloride (125 mcg/mL), edetate disodium, hypromellose, citric acid, dibasic sodium phosphate, sodium chloride, and purified water.
After priming [see DOSAGE AND ADMINISTRATION], each metered spray delivers a 0.137 mL mean volume containing 137 mcg of azelastine hydrochloride (equivalent to 125 mcg of azelastine base). The bottle can deliver 200 metered sprays.
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