Gold Member Since 2016
Wuhan Hengwo Scien-Tech Co., Ltd.

Doxorubicin HCl, Doxorubicin Hydrochloride, Dox manufacturer / supplier in China, offering Anti-Cancer Doxorubicin Hydrochloride Dox Doxorubicin HCL for Antitumor Antibiotic, Factory Supply Hot Nutrition Powders N-Acetyl-L-Tyrosin, Donepezil Nootropics Powder Donepezil HCl and so on.

(/ )

Supplier Homepage Product Pharmaceutical APIs Anti-Cancer Doxorubicin Hydrochloride Dox Doxorubicin HCL for Antitumor Antibiotic

Anti-Cancer Doxorubicin Hydrochloride Dox Doxorubicin HCL for Antitumor Antibiotic

Purchase Qty.:
(Gram)
10-19 20-49 50+
FOB Unit Price: US $1 US $0.8 US $0.5
Purchase Qty. (Gram) FOB Unit Price
10-19 US $1
20-49 US $0.8
50+ US $0.5
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: 5000kg/Month
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

Request a custom order and have something just for you!

Send Customized Request
Basic Info
  • Model NO.: CAS 25316-40-9
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • CAS: 25316-40-9
  • MW: 579.9802
  • Trademark: Biopharmchem
  • Specification: Pharmaceutical Grade
  • HS Code: 2941909000
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001, USP, BP
  • State: Solid
  • Product Name: Doxorubicin Hydrochloride, Doxorubicin HCl, Dox
  • Mf: C27h30clno11
  • Einecs: 246-818-3
  • Transport Package: as Requires
  • Origin: China
Product Description

       Anti-cancer doxorubicin hydrochloride DOX Doxorubicin HCL for Antitumor Antibiotic

Product name:doxorubicin hydrochloride,Doxorubicin HCL,DOX
CAS: 25316-40-9
EINECS: 246-818-3
MF: C27H30ClNO11
MW: 579.9802
Synonym: DOX, Hydroxydaunorubicin hydrochloride

Antineoplastic antibiotic obtained from Streptomyces peucetius. Doxorubicin Hydrochloride is a hydroxy derivative of DAUNORUBICIN.

Usage

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Advantage

Doxorubicin, epirubicin, idarubicin and valrubicin are structurally related cytotoxic antineoplastic antibiotics used in the therapy of several forms of lymphoma, leukemia, sarcoma and solid organ cancers. Doxorubicin is associated with a high rate of transient serum enzyme during therapy and to rare instances of clinically apparent acute liver injury with jaundice that can be severe and even fatal. Epirubicin and idarubicin have similar profiles of activity and adverse events as doxorubicin, but have been less commonly used and their potential for causing liver injury has been less well defined. Valrubicin is instilled directly in the bladder as treatment of refractory urinary bladder cancer, has little systemic distribution, and has not been associated with serum enzyme elevations or clinically apparent liver injury.

 
Send your message to this supplier
Avatar
Mr. Jerry
Sales
*From:
To: Mr. Jerry
*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for? Post a Sourcing Request Now

Find Similar Products By Category