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Wuhan Hengwo Scien-Tech Co., Ltd.

Fluconazole, Chemical Raw Material, Steroid Hormone manufacturer / supplier in China, offering Factory Supply of CAS 86386-73-4 as an Antifungal Fluconazole, Oral Tren Prohormone Powders Trendione Trenavar, Female Hormone Estrogen Steroids Estradiol and so on.

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Supplier Homepage Product Pharmaceutical APIs Factory Supply of CAS 86386-73-4 as an Antifungal Fluconazole

Factory Supply of CAS 86386-73-4 as an Antifungal Fluconazole

Purchase Qty.:
(g)
10-99 100+
FOB Unit Price: US $1 US $0.78
Purchase Qty. (g) FOB Unit Price
10-99 US $1
100+ US $0.78
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Production Capacity: 2000 Tons/Year
Transport Package: 1 Kg/Foil Bag
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Fluconazole
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Alias: Fluconazole
  • Einecs No: 200-659-6
  • Molecular Weight: 306.27
  • Trademark: YC
  • Origin: Hubei, China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001
  • State: Solid
  • Product Name: Fluconazole
  • CAS Registry Number: 86386-73-4
  • Molecular Formula: C13h12f2n6o
  • Appearance: White Powder
  • Specification: USD Standard
  • HS Code: 3001200010
Product Description
Factory Supply of  CAS 86386-73-4 as an Antifungal  Fluconazole
Product Name:    Fluconazole
Synonyms:    FLUCONAZOLE;FLUCONAZOLE-D4;FLUCONAZOLE-D4 (BISMETHYLENE-D4);diflucan;2,4-DIFLUORO-ALPHA, ALPHA-1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;A-(2,4-DIFLUOROPHENYL)-A-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOL-1-ETHANOL;alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol
CAS:    86386-73-4
MF:    C13H12F2N6O
MW:    306.27
EINECS:    200-659-6
Product Categories:    Active Pharmaceutical Ingredients;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;API's;Antifungal;Aromatics;Heterocycles;Pfizer compounds;Isotope Labelled Compounds;DARICON
Mol File:    86386-73-4.mol
Fluconazole Structure
Anti-fungal infection drug    Fluconazole is a novel kind triazole drug of anti-fungal infection which was first successfully developed by the American Pfizer with broad-spectrum anti-fungal effect. It belongs to a kind of systemic anti-fungal products and has high selectivity on the inhibitory effect of the fungal cytochrome P450-dependent enzyme. It is also a kind of potent and specific inhibitor for the fungi alcohol synthesis. Clinically it is mainly used for the treatment of vaginal candidiasis, thrush, atrophic oral candidiasis, fungal meningitis, pulmonary fungal infections, abdominal infections, urinary tract infections and skin fungi infection. 
The main indication for fluconazole as follows:
1, systemic candidiasis: including candidemia, disseminated candidiasis and other forms of invasive Candida infections such as the peritoneum, endocardium, lungs and urinary tract infections. It can also be applied to patients of malignant tumors, special-care patients, patients who received radiotherapy, chemotherapy or immunosuppressive therapy as well as patients who are susceptible to other factors such as infection of Candida. It can also be used for prevention of the occurrence of candida infection for bone marrow transplant patients upon receiving cytotoxic drugs treatment or radiation treatment.
2, cryptococcosis: including cryptococcal meningitis and the cryptococcal infection in other parts (such as lung, skin). It can be applied to the patient of normal immune function, AIDS patients as well as patient of suppressed immune function due to organ transplant and other reasons. AIDS patients can administer this kind of drug for maintenance therapy and prevention of the relapse of cryptococcal disease.
3, mucosal candidiasis: including oropharyngeal, esophageal, non-invasive bronchial mucosal candidiasis, pulmonary candidiasis, Candida urine disease, mucocutaneous and chronic atrophic oral candidiasis. It can be applied to patients of both normal immune function and with impaired immune function.
4, fluconazole can be used as substitute of itraconazole for the treatment of blastomycosis and histoplasmosis.
5, it can be used for the treatment of acute or recurrent vaginal candidiasis.
6, for leukemia patients or patients of other malignant tumor who is susceptible to fungal infection upon undergoing chemotherapy or radiotherapy can apply it as means of preventive treatment.
7, it can be used for the treatment coccidioidomycosis.
8, it can be used for treatment of fungal skin disease including fungal skin infections such as body ringworm, tinea pedis, tinea versicolor, tinea capitis, onychomycosis and nail ringworm.
9, fluconazole can also be used for the treatment of skin chromomycosis.
In August 2002, the voriconazole (Pfizer) which enters in the United States is the further structural modified derivative of fluconazole with its antibacterial activity against pathogenic yeast being higher than fluconazole. Some case reports have demonstrated that the drug can successfully cure some rare fungal disease.
Chemical Properties    It appears as white to yellow-white crystalline powder and is slightly smelly with bitter taste. It is easily soluble in glacial acetic acid, methanol or ethanol, hardly soluble in water and almost insoluble in ether with the melting point being 137~141.6 ºC, or melting point being 138~140 ºC (derived from ethyl acetate-hexane).
 
Uses    This product belongs to fluorinated triazole antifungal drug with the antifungal spectrum being similar as ketoconazole but antifungal activity being higher than ketoconazole. Its mechanism of action is through inhibition of essential component of the fungal cell membrane, the ergosterol biosynthesis enzyme, blocking the ergosterol synthesis and breaking the integrity of the fungal cell wall, further inhibiting their growth and reproduction. The product has potent antifungal activity against Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum and epidermophyton.
Chemical Properties    White to Off-White Solid
Usage    Labelled Fluconazole (F421000). Used as an antifungal.
Usage    anticholinergic
Usage    For the treatment of fungal infections.

Company Profile

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