Gold Member Since 2016
Wuhan Hengwo Scien-Tech Co., Ltd.

Tacrolimus, Chemical Raw Material, Steroid Hormone manufacturer / supplier in China, offering High Purity Anti-Inflammatory Steroid Powder Tacrolimus, Natural Plant 99% Min Extract Silymarin CAS 65666-07-1, High Purity Anabolic Steroid Hormone Powder Drostanolone Propionate Masteron and so on.

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Supplier Homepage Product Pharmaceutical APIs High Purity Anti-Inflammatory Steroid Powder Tacrolimus

High Purity Anti-Inflammatory Steroid Powder Tacrolimus

Purchase Qty.:
(g)
10-99 100+
FOB Unit Price: US $1 US $0.78
Purchase Qty. (g) FOB Unit Price
10-99 US $1
100+ US $0.78
Get Latest Price
Port: Hong Kong, Hong Kong
Production Capacity: 2000 Tons/Year
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Tacrolimus
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Alias: Prograf; Protopic; Tsukubaenolide; Advagraf
  • Molecular Formula: C44h69no12
  • Appearance: White Powder
  • Trademark: Fuluobiotech
  • Specification: USD Standard
  • HS Code: 3001200010
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001
  • State: Solid
  • Product Name: Tacrolimus
  • CAS Registry Number: 104987-11-3
  • Molecular Weight: 804.02
  • Grade: Pharmaceutical Grade
  • Transport Package: 1 Kg/Foil Bag
  • Origin: Hubei, China
Product Description
High Purity Anti-Inflammatory Steroid Powder Tacrolimus

 
Product NameTacrolimus
AliasPrograf; Protopic; Tsukubaenolide; Advagraf 
CAS Registry Number104987-11-3
Molecular FormulaC44H69NO12
Molecular Weight804.02
Purity99%
GradePharmaceutical Grade
Appearancewhite crytalline powder


Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.Tacrolimus anhydrous is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of tacrolimus anhydrous is as a Calcineurin Inhibitor.

Anhydrous from of tacrolimus, a macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.

Usage:
Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα.
 
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