USP Grade Min High Quality Pharmaceuticals and Nutraceuticals L-Tyrosine
|FOB Unit Price:||US $1 US $0.78|
|Purchase Qty. (g)||FOB Unit Price|
|Port:||Hong Kong, Hong Kong|
|Production Capacity:||2 000tons/Year|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: L-Tyrosine
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Alias: L-Tyrosine
- Einecs No: 200-460-4
- Molecular Weight: 181.19
- Trademark: Biopharmchem
- Specification: USD Standard
- HS Code: 3001200010
- Powder: Yes
- Certification: GMP, HSE, ISO 9001
- State: Solid
- Product Name: L-Tyrosine
- CAS Registry Number: 60-18-4
- Molecular Formula: C9h11no3
- Appearance: White Powder
- Transport Package: 1 Kg/Foil Bag
- Origin: Hubei, China
Synonyms:3-(4-hydroxyphenyl)-l-alanine;2-amino-3-(4-hydroxyphenyl)-propanoic acid;2-amino-3-(p-hydroxyphenyl)propionic acid;4-hydroxyphenylalanine;Fema 3736;H-l-tyr-oh;H-tyr-oh;L-3-[4-hydroxyphenyl]alanine
Product categories:Food and feed additive;Tyrosine [tyr, y];Amino acids;Amino acids and derivatives;Alpha-amino acids;Biochemistry;Nutritional supplements;L-amino acids;Amino acids;Norcuron;Amino;Inhibitors
Tyrosine in human metabolism tyrosine is an amino acid building blocks of proteins, and having a side chain having an aromatic ring of ionization, is addicted to the aqueous, tyrosine in the human and animal bodies is generated by the hydroxylation of phenylalanine, so when phenylalanine nutrition is adequate, it is non essential amino acid.
Catabolism of tyrosine is firstly catalyzed by tyrosine aminotransferase in the liver , then transform into hydroxyphenyl pyruvate, the enzyme needs coenzyme pyridoxal phosphate .Hydroxyphenyl pyruvate by hydroxyl phenylketonuria hydroxylase role, while oxidative decarboxylation and metastasis, and the benzene ring ortho hydroxylation of the side chain of pyruvate to generate the urine black acid (glyoxylic acid).The enzyme is a protein containing copper metal, needing ascorbic acid and coenzyme consume molecular oxygen.Black acid in urine in the urine black acid dioxygenase (urine black acid oxidase) catalyzes the cleavage benzene to produce maleic acid acetoacetate;Enzyme is a protein ferrous metals, the reactions require oxygen molecule to be involved in .Maleic acid via the corresponding acetoacetate isomerase role into fumarylacetoacetate need coenzyme glutathione.Finally, from the corresponding hydrolase hydrolyzed as fumaric acid and acetyl acid, so tyrosine is both glycogeneticr and ketogenic amino acids.
Tyrosine kinase tyrosine kinase , enzyme catalytic in peptide chain tyrosine residue (loci) phosphorylated,plays an important role in biological metabolism and cell communication, and molecular weight of 56,000, endometrial bound enzyme.The enzyme consists of two domains, a catalytic domain, accounting for most of the enzyme molecules, which contains two tyrosine phosphorylation sites and a c-terminal ;The other is the regulatory domain (i.E.Sh2 domain), containing the n-terminal myristoylation, serine phosphorylation site and homologous regions.
Tyrosine phosphorylation sites of the catalytic domain shows a great relation to tyrosine kinase activity , if these sites are phosphorylated, tyrosinekinase activity would be inhibited;On the contrary, if the phosphorylation of tyrosyl acid sites with phosphatase to dephosphorylate, the kinase activity can be significantly increased.Tyrosine phosphorylation sites near the ends of the c, but with different tyrosine kinase gene expression (e.G., c-src gene product family), the location of these sites is different, if it is missing out, it kinases is activated.In addition, the polyomavirus middle t-antigen gene expression and c-src tyrosine kinase binding sites in the vicinity of 527 tyrosine at the site, since it is too close to this site , the formation of a steric hinders the phosphorylation site, it increases the kinase activity.
Sh2 domain in addition to homologous regions , other parts are of the large differences in structure, so it is possible to act with different regulating factors, plays a role in regulating the kinase activity.
Hemical properties white needle crystal or crystalline powder, odorless, bitter taste, mp334 ºc (decomposition) is insoluble in water (0.04%, 25 ºc), insoluble in ethanol, ether and acetone, soluble in dilute acid or base .The isoelectric point of 5.66..