Gold Member Since 2016
Wuhan Hengwo Scien-Tech Co., Ltd.

Melatonine, Melaton, Sleeps manufacturer / supplier in China, offering Sleeps Nutritional Supplemen Melatonine for Family Medicine, Oral Tren Prohormone Powders Trendione Trenavar, Female Hormone Estrogen Steroids Estradiol and so on.

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Sleeps Nutritional Supplemen Melatonine for Family Medicine

Purchase Qty.:
(grams)
10-99 100+
FOB Unit Price: US $10 US $8
Purchase Qty. (grams) FOB Unit Price
10-99 US $10
100+ US $8
Get Latest Price
Production Capacity: 200kg/Month
Transport Package: Disguised Packing for Delivery Guarantee!
Payment Terms: Western Union, Money Gram

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Basic Info
  • Model NO.: CAS: 73-31-4
  • Customized: Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • Mf: C13h16n2o2
  • Einecs: 200-797-7
  • Appearance: White Powder
  • Specification: Pharmaceutical Grade
  • HS Code: 2937390000
  • Powder: Yes
  • Certification: GMP, ISO 9001, BP
  • State: Solid
  • CAS: 73-31-4
  • MW: 232.28
  • Assay: 99%
  • Trademark: Biopharmchem
  • Origin: China
Product Description
Sleeps Nutritional Supplemen Melatonine for Family Medicine
Melatonine

Product Name:    Melatonine
Synonyms:    Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)ethyl];Melatonin(N-Acetyl-5-methoxytryptamine);n-(2-(5-methoxy-1h-indol-3-yl)ethyl)-acetamid;n-(2-(5-methoxyindol-3-yl)ethyl)-acetamid
CAS:    73-31-4
MF:    C13H16N2O2
MW:    232.28
EINECS:    200-797-7
Assay: 99%
Appearance:White powder
Grade: Pharmaceutical Grade

A hormone secreted by the pineal gland cells

    Melatonin is a hormone secreted by the pineal gland, and its chemical structure was 5-methoxy-N-acetyl tryptamine, the physiological function of inhibiting gonad, thyroid, adrenal gland, parathyroid gland and pituitary function, inhibit precocious puberty, reduce pituitary Melanotropin secretion; and has a central nervous system function, can improve the convulsion the threshold, cause drowsiness. When pinealectomy after the animal experiment showed hyperplasia of the glands, weight increase, especially sex and sexual organs of immature rats early, pituitary secretion of LH and FSH increased, increasing secretion of thyroid and adrenal cortex hormone melatonin. More reduced pituitary MSH and whiten the skin of this role. Effects on the central nervous system, in the human EEG showed slow rhythm, increased seizure threshold, sleepiness, but does not affect their behavior and personality, of temporal lobe epilepsy and Ba Jinsen disease can reduce the motor nerve Abnormal EEG changes.

Pineal hormone synthesis and release    

Pineal cells obtain tryptophan from blood circulation and become 5-hydroxytryptophane catalyzed by hydroxylase and 5-hydroxytryptophane turns into 5-hydroxytryptamine after decarboxylated by decarboxylase. There are three possible changes for 5-hydroxytryptamine: for the first part it may turn into 5-hydroxyl-benzpyrole acetic acid when deaminated by monoamine oxidase; for another part, some 5-hydroxytryptamine will leave the pineal cell and be taken in by sympathetic nerve ending and stored with neurotransmitter and noradrenalin; for the remaining part, the 5-hydroxytryptamine will be acetylated by N-acetyl-5-hydroxy tryptamine transferase and then be o-methoxy by hydroxylation indole-o-methyl converzyme, finally forming melatonin. After being synthesized, melatonin will be released by cells and enter into blood circulation through cerebrospinal fluid or directly, where noradrenalin may strengthen the synthesis, the speed of which depends on activity of hydroxylase in liver microsomes. Catalyzed by the hydroxylase, 6-hydroxylmelatonin is formed, soon afterwards it combines with glucuronic acid and sulfate, excreting through urine.
 
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