Gold Member Since 2016
Wuhan Hengwo Scien-Tech Co., Ltd.

Bimatoprost, Chemical Raw Material, Steroid Hormone manufacturer / supplier in China, offering Hot Sale Pharmacetical Raw Materials 155206-00-1 Bimatoprost, Oral Tren Prohormone Powders Trendione Trenavar, Female Hormone Estrogen Steroids Estradiol and so on.

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Hot Sale Pharmacetical Raw Materials 155206-00-1 Bimatoprost

Purchase Qty.:
(g)
10-99 100+
FOB Unit Price: US $1 US $0.78
Purchase Qty. (g) FOB Unit Price
10-99 US $1
100+ US $0.78
Get Latest Price
Production Capacity: 200 Tons/Year
Transport Package: 1 Kg/Foil Bag
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Bimatoprost
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Alias: Bimatoprost
  • Einecs No: C25h37no4
  • Molecular Weight: 415.57
  • Trademark: YC
  • Origin: Hubei, China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001
  • State: Solid
  • Product Name: Bimatoprost
  • CAS Registry Number: 155206-00-1
  • Molecular Formula: C25h37no4
  • Appearance: White Powder
  • Specification: USD Standard
  • HS Code: 3001200010
Product Description
Hot Sale Pharmacetical Raw MaterialsBimatoprost 155206-00-1
Product Name:    Bimatoprost
Synonyms:    N-ETHYL-9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z, 13E-DIEN-1-AMIDE;LUMIGAN;BIMATOPROST;BIMATOPROST(TM);17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ETHYL AMIDE;BIMATOPROST(LUMIGAN);17-phenyl-tri-norprostaglandin f2α-ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
CAS:    155206-00-1
MF:    C25H37NO4
MW:    415.57
EINECS:    
Product Categories:    Prostaglandins;Prostaglandin;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Arachidonic Acid Cascade;Lipids in Cell Signaling;Lumigan;Inhibitors;Benzotriazoles ,Others ,Benzoxazines
Mol File:    155206-00-1.mol
Bimatoprost Structure
Chemical Properties    Crystalline Solid
Usage    Antiglaucoma. Synthetic prostamide; structurally related to prostaglandin F2a.
Usage    Antiglaucoma. Synthetic prostamide; structurally related to prostaglandin F2α.
Usage    Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It ha
Usage    Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.
Glaucoma Drug    Bimatoprost is a synthetic amide F2α derivative ,it can selectively simulate the effect forefront amines produced by the body, which make aqueous humor production rate increase aqueous outflow resistance is reduced, by increasing the amount of aqueous outflow of the uveoscleral and trabecular Netcom channel to reduce intraocular pressure (IOP),it is considered to be the most effective hypotensive drug of topical ocular anti-glaucoma drugs,it is suitable for the treatment of open-angle glaucoma (POAG) or invalid elevated intraocular other ocular hypotensive medications compression syndrome (OHT) patients.
Side effects    1. to deepen the color of the iris, blepharitis, eye irritation and pain; black eyelashes thicker growth; conjunctival hyperemia, temporarily punctate corneal epithelial erosion, eyelid edema and erythema; rash. 
2. rare respiratory disorders, asthma exacerbations, iritis, uveitis, eyelid skin darkening.
3. very rare chest pain, pharyngitis.
4. eye itching, allergic conjunctivitis, cataract, conjunctival edema, secretions, photophobia, superficial punctate keratitis, headache, high blood pressure.
Glaucoma commonly used drugs    1. prostaglandin derivatives such as latanoprost (Xalatan), bimatoprost (trade name Lumigan) and travoprost (Travatan) can increase outflow of aqueous humor uveoscleral . Bimatoprost also increases trabecular outflow. 
2. topical β-adrenergic such as timolol, levobunolol (Betagan), and betaxolol can decrease receptor antagonist of aqueous humor production of ciliary body . 
3. Alpha2-adrenergic agonists such as brimonidine (Alphagan) with dual working mechanism, can reduce aqueous humor production and increase trabecular outflow.
4. one case of the selective reduction similar to epinephrine and dipivefrin (Propine) increase outflow of aqueous humor through trabecular meshwork and possibly through uveoscleral outflow pathway, probably by a β2-agonist action.
5. miotic agents (parasympathomimetics), if ciliary muscle contraction Roca works, it can tighten the trabecular and allow increaseing outflow of aqueous humor. Ecothiopate is used for chronic glaucoma.
6. dorzolamide (Trusopt), brinzolamide (Azopt), by inhibiting carbonic anhydrase acetazolamide of ciliary body, reduce aqueous humor secretion of carbonic anhydrase inhibitors.
7. Physostigmine is also used to treat glaucoma and delayed gastric emptying.
Bimatoprost - timolol maleate compound eye drops    In July 2006 , bimatoprost-timolol maleate compound eye drops developed by the United States company obtained approval from the European drug regulatory authority for reducing intraocular pressure or ocular hypertension of open-anglepatients glaucoma patients who do not respond adequately to the β-blockers or prostaglandin like treatment .
The compound eye drops containing 0.03% bimatoprost and 0.5% timolol maleate, once a day administration is able to provide clinically effective pressure control, the effect is better than single Bima latanoprost or timolol maleate. Clinical trials prove that the drug has an excellent tolerability, including the incidence of ocular hyperemia40% lower compared to single bimatoprost .

Company Profile

Wuhan Hengwo Scien-Tech Co., Ltd,is a leading supplier of raw steroids in China.We specialize in producing and seliing various kinds of
Raw steroid powders,semi-finished liquid injectable/oral steroids,polypeptide and natural hormones,Cortiscosteroids,progestational
hormones,etc.With High quality raw materials and advanced clean workshop,as well as strict quality control,our steroid hormones got many good feedback from all over the world.


Technique support is available whenever you have questions in making the steroid powders into finished products or when using.With over 14 years'
experiences exporting steroids worldwide,we have a high customs pass rate,also packages will be free resent to you in case it get seized."Delivery
guarantee,Quality service"is our promisr for you!

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