CAS 65-23-6/12001-77-3pyridoxine Nutrition Supplement Vitamin B6
|FOB Unit Price:||US $1 US $0.78|
|Purchase Qty. (g)||FOB Unit Price|
|Production Capacity:||200 Tons/Year|
|Transport Package:||1 Kg/Foil Bag|
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- Model NO.: Vitamin B6
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Alias: Yohimbine HCl
- Einecs No: 200-399-3
- Molecular Weight: 244.31
- Trademark: YC
- Origin: Hubei, China
- Powder: Yes
- Certification: GMP, HSE, ISO 9001
- State: Solid
- Product Name: Yohimbine Hydrochloride
- CAS Registry Number: 8059-24-3
- Molecular Formula: C10h16n2o3s
- Appearance: White Powder
- Specification: USD Standard
- HS Code: 3001200010
Product Name: Vitamin B6
Mol File: 8059-24-3.mol
Vitamin B6 Structure
B vitamins, vitamin B6, also known as "anti dermatitis vitamins"". One of the vitamins B. Genus of pyridine derivatives, including pyridoxine (pyridoxine), pyridoxal, pyridoxamine (pyridoxal) (pyridoxamine) three compounds in food which can exist in the form of mutual transformation. But the plants in the vitamin B6 for human and animal in vivo and pyridoxine, pyridoxal and pyridoxamine are. Human intestinal bacteria can also synthesize pyridoxine, pyridoxine in the human body can be transformed into pyridoxal and pyridoxamine, the latter two cannot change into pyridoxine. The three have the same physiological activity. Vitamin B6 in the human body is rapidly converted to pyridoxal phosphate compound, which plays an important role in the metabolism of amino acid, COA decarboxylase, transaminase, kynurenine enzyme, enzyme hydration desulfurization, ada. Carbohydrate and fat metabolism, the activity of the central nervous system, and the necessary coenzyme for the production of red blood cells. Vitamin B6 is widely found in nature. The yolk, fish, meat, seeds, grains (germs) are more abundant, and the general diet is not deficient in the vitamin. Vitamin B6 deficiency can cause dermatitis, convulsions, anemia and other symptoms. Vitamin B6 is mainly used for radiation sickness and anticancer drugs caused by pregnancy, vomiting, vitamin B6 deficiency, seborrheic dermatitis, cheilitis, stomatitis and acute and chronic eczema, also can be used for food additives, feed additives and cosmetics.
Pharmacological action in vivo with ATP through the enzyme can produce reactive pyrazine and phosphoric acid pyrazole, the latter as coenzyme, to protein, carbohydrates, lipids play a variety of metabolic function. Vitamin B6 is also involved in the conversion of tryptophan to niacin or 5- serotonin. In the gastrointestinal tract, it is absorbed mainly by the jejunum, which binds to plasma proteins completely and T1/2 for up to 15~20 days. It is metabolized through the liver and excreted by the kidneys. It can also be excreted by hemodialysis. The first step in the synthesis of heme is the connection of glycine with the phosphate phosphate, which is converted to vitamin B6, and then combined with the succinate coenzyme A in the delta amino acid synthetase to combine into - amino - gamma - valerate (ALA). And then through a series of enzymes, eventually forming protoporphyrin in mitochondria. Iron enters the porphyrin ring and binds to protoporphyrin to become heme. Reduce the stimulation of chemoreceptor, alleviate the symptoms of nausea and vomiting, and promote the growth of white blood cells. External use can improve local nerve function and reduce inflammation.
The physiological function vitamin B6 is the coenzyme of transaminase and amino acid decarboxylase, which promotes the absorption of amino acid and the synthesis of protein, which is essential for the growth of cells. Participate in many kinds of metabolism in vivo.
Vitamin B6 deficiency, vitamin B6 deficiency, including the narrow range of vitamin B6 deficiency and vitamin B6 dependence two. Vitamin B6 deficiency in the narrow sense refers to the deficiency of vitamin B6 or the loss of the activity of vitamin B6 resulting from the ingestion of certain vitamins in food. Vitamin B6 dependence refers to the amount of vitamin B6 a patient needs to ingest healthy people. However, vitamin B6 deficiency is still present, which is a genetic disorder. Normal diet rarely causes vitamin B6 deficiency. See the current clinical vitamin B6 deficiency due to vitamin B6 antagonists such as isoniazid, cycloserine, penicillamine caused by a few; due to suffering from malignant tumor, liver, kidney disease, chronic alcoholism; anorexia of inappropriate feeding infants and elderly people may get sick.
The main clinical manifestations of skin and mucosal inflammation, common seborrheic dermatitis, desquamation and stomatitis, glossitis, ophthalmia etc.. The second is mental and neurological symptoms, such as nervousness, depression, lethargy, nausea, vibration, loss of position, and peripheral neuritis. Vitamin B6 deficiency induces heme synthesis and folic acid metabolism caused by anemia, low pigment small cell anemia, but not the lack of iron, but iron utilization is not sufficient, the excess iron in ferritin deposition in the form of liver, spleen, bone marrow, liver, clinical appearance of Pi Zhongda. In addition, vitamin B6 deficiency in infants and young children can also produce growth retardation, emaciation, weight loss and other abnormal growth and development.
The diagnosis of vitamin B6 deficiency in the narrow sense is based on medical history, symptoms, signs, and necessary laboratory tests. After oral tryptophan 100 mg/kg, the excretion of uric acid in urine was measured, and the nutritional status of vitamin B6 in the body was measured. The excretion rate of vitamin B6 in the 6 hours and 24 hours was higher than that in 25mg and 75mg, respectively, and the deficiency of vitamin B in the body was considered.
The most effective way to treat vitamin B6 deficiency is to supplement large amounts of vitamin B6. Take a large number of isoniazid or Penicillium amine patients should take appropriate amount of vitamin B6, can prevent isoniazid caused by peripheral neuritis and Penicillium ammonia caused by optic neuritis. Patients with a history of epilepsy must be treated with vitamin B6 regularly to prevent seizures.
Indications (1) for lack of vitamin B6 (vitamin B6 deficiency can cause urinary xanthine acid, sideroblastic anemia, nervous system disease, seborrheic dermatitis and cheilosis) treatment, treatment of isoniazid poisoning; also can be used for radiation sickness and anticancer drugs caused by pregnancy, vomiting, seborrheic dermatitis.
(2) total parenteral nutrition and vitamin B6 supplementation due to inadequate intake of malnutrition and progressive weight loss.
(3) treat convulsions in infants or take them to pregnant women to prevent convulsions.
Effect Jianpi Qi, nourishing the mind and soothe the nerves.
1. for lung and spleen qi deficiency. This product can is the treatment of Spleen Qi, loss of appetite, fatigue, dizziness, nausea, vomiting, muscle flaccidity, skin numbness of lung spleen deficiency syndrome
2. for palpitation, insomnia. This product can be used in the treatment of Yangxinanshen, palpitation, heart qi and blood deficiency caused by malnutrition of restlessness, insomnia, irritability symptoms such as numbness.
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