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Wuhan Hengwo Scien-Tech Co., Ltd.

Phentolamine Mesilate, Chemical Raw Material, Steroid Hormone manufacturer / supplier in China, offering CAS 65-28-1 Factory Supply Pharmaceutical Intermediate Phentolamine Mesilate, Test Enanthate Testosterone Enanthate for Bodybuilding, 99% Good Quality Powder Methyltrienolone and so on.

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CAS 65-28-1 Factory Supply Pharmaceutical Intermediate Phentolamine Mesilate

Purchase Qty.:
(g)
10-99 100+
FOB Unit Price: US $1 US $0.78
Purchase Qty. (g) FOB Unit Price
10-99 US $1
100+ US $0.78
Get Latest Price
Production Capacity: 200 Tons/Year
Transport Package: 1 Kg/Foil Bag
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Phentolamine mesilate
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Alias: Phentolamine Mesilate
  • Einecs No: 200-604-6
  • Molecular Weight:  377.46
  • Trademark: YC
  • Origin: Hubei, China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001
  • State: Solid
  • Product Name: Phentolamine Mesilate
  • CAS Registry Number: 65-28-1
  • Molecular Formula: C18h23n3o4s
  • Appearance: White Powder
  • Specification: USD Standard
  • HS Code: 3001200010
Product Description
CAS 65-28-1 Factory Supply Pharmaceutical Intermediate Phentolamine Mesilate 
Product Name:    Phentolamine mesilate
Synonyms:    REGITIN;REGITIN MESYLATE;PHENTOLAMINE MESILATE;PHENTOLAMINE MESYLATE;PHENTOLAMINE METHANESULFONATE;PHENTOLAMINE METHANESULFONATE SALT;VASOMAX;m-(n-(2-imidazolin-2-ylmethyl)-p-toluidino)-phenomonomethanesulfonate(sal
CAS:    65-28-1
MF:    C18H23N3O4S
MW:    377.46
EINECS:    200-604-6
Product Categories:    ACTIVE PHARMACEUTICAL INGREDIENTS;Erectile Dysfunction;Diagnostic;Intermediates & Fine Chemicals;Pharmaceuticals;Adrenoceptor;API;Pharmaceutical raw material;Regitine;pharmaceutical
Mol File:    65-28-1.mol
Phentolamine mesilate Structure
Chemical Properties    Crystalline Solid
Usage    Phentolamine Mesylate is a nonselective alpha-adrenergic antagonist with IC50 of 0.1 μM
Usage    An adrenergic blocking agent. An antihypertensive. Used for the treatment of pheochromocytoma.
An adrenergic receptor blocker of erectile dysfunction (erectile dysfunction ED) is a common and important sexual dysfunction, Department of Urology disease. Epidemiological data suggest that the incidence of male ED is more common, and is associated with increased age and dyslipidemia, hypertension, coronary artery disease and diabetes and other diseases. At present, about 152 million males worldwide suffer from ED, and with the aging of human society, it is predicted that by 2025, 322 million males will suffer from this sexual dysfunction worldwide. Phentolamine, a non selective adrenergic a receptor blocker, can reduce peripheral vascular resistance and increase peripheral vascular blood flow. In the treatment of male erectile dysfunction, the drug can act on the a receptor in erectile tissue, relax arterioles and capillaries, increase blood supply to the corpus cavernosum, and promote and enhance erectile function. The United States developed Shering company Vasomax (phentolamine mesylate tablets) has been listed in some Latin American countries, for the treatment of male erectile dysfunction. In addition to oral administration, phentolamine is currently the commonly administered route of injection. Because of the pain and inconvenience of the injection, the patient has poor compliance with medication and may also have adverse effects such as fibrosis of the injected site and fibrosis, which is not suitable for repeated use of drugs.
After years of clinical verification, phentolamine mesylate is mainly used for sexual dysfunction, especially for treatment of erectile dysfunction, the effect is remarkable. Capsules and tablets used as oral preparations are more popular with consumers because of their convenience in taking and carrying.
At the same time, Phentolamine Mesylate for Injection is the clinical common alpha adrenergic receptor blocker, can antagonize circulating epinephrine and norepinephrine, expand blood vessel and reduce peripheral vascular resistance, high blood pressure for the diagnosis of pheochromocytoma and its treatment induced seizures, left ventricular failure and prevent skin necrosis.
Phentolamine mesylate (phentolamine, mesylate, PM) is an adrenergic receptor blocker, and has effects on alpha 1 and alpha 2 receptors. Tablets, capsules and injections have been developed.
Phentolamine mesylate tablets for alpha receptor blocker competitive potential, by blocking vascular smooth muscle alpha l receptor alpha 2 receptors as well as possible, resulting in decreased peripheral resistance, vascular dilatation, the corpus cavernosum smooth muscle to relax, let more blood flows into the sponge body, while suppressing the flow of blood in the sponge lead, erection. Oral use of phentolamine is low and its oral preparation is clinically useful in the treatment of erectile dysfunction.
Phentolamine Mesylate for Injection is the clinical common alpha adrenergic receptor blocker, can antagonize circulating epinephrine and norepinephrine, expand blood vessel and reduce peripheral vascular resistance, used for the diagnosis and treatment of pheochromocytoma which caused by hypertension, left ventricular failure and prevent skin necrosis. The drug is a variety of Chinese Pharmacopoeia 2005 edition.
The utility model is mainly used for diseases of the cardiovascular system, diabetes, nephrosis, toxic intestinal paralysis, acute respiratory distress syndrome, capillary bronchitis, severe asthma, etc..

Company Profile

Wuhan Hengwo Scien-Tech Co., Ltd,is a leading supplier of raw steroids in China.We specialize in producing and seliing various kinds of
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Technique support is available whenever you have questions in making the steroid powders into finished products or when using.With over 14 years'
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