Pharmaceutical Raw Material Altretamine for Anticancer CAS 645-05-6
|10-19 20-49 50+|
|FOB Unit Price:||US $1 US $0.8 US $0.5|
|Purchase Qty. (Gram)||FOB Unit Price|
|Port:||Hong Kong, Hong Kong|
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- Model NO.: CAS 645-05-6
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- CAS: 645-05-6
- Mf: C9h24n6
- Trademark: Biopharmchem
- Specification: Pharmaceutical Grade
- HS Code: 3912310000
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP
- State: Solid
- Product Name: Altretamine
- Einecs No: 211-428-4
- MW: 216.3271
- Transport Package: as Requires
- Origin: China
Pharmaceutical raw material Altretamine for anticancer CAS 645-05-6
Product name: altretamine
Altretamine (trade name Hexalen) is an antineoplastic agent.
It is indicated for use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with cisplatin and/or alkylating agent-based combination.
It is not considered a first-line treatment, but it can be useful as salvage therapy. It also has the advantage of being less toxic than other drugs used for treating refractory ovarian cancer.
Side effects include nausea, vomiting, anemia and peripheral sensory neuropathy.
Combination with pyridoxine (vitamin B6) decreases neurotoxicity but has been found to reduce the effectiveness of an altretamine/cisplatin regime. MAO inhibitor can cause severe orthostatic hypotension when combined with altretamine; and cimetidine can increase its elimination half-life and toxicity.
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