Gold Member Since 2016
Wuhan Hengwo Scien-Tech Co., Ltd.

Misoprostol, Chemical Raw Material, Steroid Hormone manufacturer / supplier in China, offering 99% Purity Steroid Powder for Antiulcerative 59122-46-2 Misoprostol, Oral Tren Prohormone Powders Trendione Trenavar, Female Hormone Estrogen Steroids Estradiol and so on.

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Supplier Homepage Product Pharmaceutical APIs 99% Purity Steroid Powder for Antiulcerative 59122-46-2 Misoprostol

99% Purity Steroid Powder for Antiulcerative 59122-46-2 Misoprostol

Purchase Qty.:
(g)
10-99 100+
FOB Unit Price: US $1 US $0.78
Purchase Qty. (g) FOB Unit Price
10-99 US $1
100+ US $0.78
Get Latest Price
Production Capacity: 2000 Tons/Year
Transport Package: 1 Kg/Foil Bag
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: Misoprostol
  • Customized: Customized
  • Suitable for: Adult
  • Purity: >99%
  • Alias: Misoprostol
  • Einecs No: C22h38o5
  • Molecular Weight: 382.54
  • Trademark: YC
  • Origin: Hubei, China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001
  • State: Solid
  • Product Name: Misoprostol
  • CAS Registry Number: 59122-46-2
  • Molecular Formula: C22h38o5
  • Appearance: White Powder
  • Specification: USD Standard
  • HS Code: 3001200010
Product Description
99% Purity Steroid Powder Misoprostol for Antiulcerative 59122-46-2
Product Name:    Misoprostol
Synonyms:    CYTOTEC;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID, METHYL ESTER;(11A,13E)-(-)-11,16-DIHYDROXY-16-METHYL-9-OXO-PROST-13-EN-1-OIC ACID METHYL ESTER;(11alpha,13e)-(+)-11alpha,16-dihydroxy-16-methyl-9-oxoprost-13e-en-1-oic acid methyl ester;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1;(+/-)-15-DEOXY-(16R,S)-16-HYDROXY-16-METHYL-PROSTAGLANDIN E1, METHYL ESTER;SC-29333
CAS:    59122-46-2
MF:    C22H38O5
MW:    382.54
EINECS:    
Product Categories:    Active Pharmaceutical Ingredients;Prostaglandins;Prostaglandin;Fatty Acid Derivatives & Lipids;Glycerols;Intermediates & Fine Chemicals;Pharmaceuticals;Prostanoid receptor and related;API;Inhibitors
Mol File:    59122-46-2.mol
Misoprostol Structure
Chemical Properties    White Solid
Usage    antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Usage    A cytoprotective prostaglandin PGE1 analogue
Pharmacological effects of misoprostol and Cytotec, Miso Fpoter, Miso Preuss Thor, in 1985 the United States listed for the first time, is a synthetic prostaglandin E1 analogue, the appearance of pale yellow viscous liquid, very difficult to dissolve in water, can be mixed with ethanol, ether and chloroform. Unstable at room temperature. Is a new type of progestin, for the synthesis of prostaglandin E1 derivatives can stimulate mucus and bicarbonate secretion, promote mucosal blood flow, and so on gastric and duodenal mucosal protective effect, conducive to ulcer healing. It can inhibit the secretion of gastric acid, histamine, five peptide gastrin and food stimulation, and the secretion of gastric acid and pepsin. In addition, because of its prostaglandin E1 role, it can make cervical collagen degradation, softening of fibrous tissue, but also can cause uterine smooth muscle, colon contraction. At present, the combination of mifepristone and mifepristone is widely used in termination of early pregnancy, and can also be used for induction of labor in the middle term.
With good oral absorption, F is about 70% ~ 80%, absorbs quickly to esterified pharmacologically active misoprostol acid. After oral administration of single dose, Tmax ranged from 0.5 to 10h. PPB ranged from 80% to 90%. Quick clearance, T1/2 is 1.5 ~ 1.7h. Mainly distributed in the body liver, kidney, stomach and large intestine. 75% of the dosage was excreted in the urine, 15% excreted by faeces, and excreted about 56% in the urine of 8h, which did not affect the enzyme activity of the liver, and was not found to interact with other drugs.
It is also used in the treatment of duodenal ulcer and gastric ulcer, and can also be used for acute gastric mucosal damage and bleeding, stress ulcer, especially for the treatment and prevention of oral ulcer caused by nonsteroidal anti-inflammatory drugs. The mechanism of the inhibition of gastric acid secretion has not been elucidated. To protect the gastric mucosa from injury is more effective than cimetidine. The major adverse effects of misoprostol were watery stools or diarrhea, with a 8% incidence, while others had mild transient nausea, headache, dizziness, and abdominal discomfort. Pregnant women and prostaglandins are forbidden. Patients with cerebrovascular or coronary artery disease should be used with caution.
Chemical properties: pale yellow viscous liquid. Miscible with ethanol, ether, or chloroform, insoluble in water or hexane. At room temperature, it is very unstable and will undergo differential thermal isomerization into a 8- isomer. Extremely sensitive to Ph values, taking 11 alpha hydroxy groups in acidic and alkaline forms and converting them into type A prostaglandins and isomerization to type B prostaglandins. But in the dispersion system of hydroxypropyl methylcellulose, it is stable and can be stored at room temperature. Acute toxicity of LD50 rats, mice (mg/kg),:40 ~ 62, 70~160 intraperitoneal injection, 81~100, 27~138 oral.
The first use of chemical synthesis of prostaglandins E1 anti ulcer drugs, has great effect for inhibiting gastric acid secretion and prevent the formation of ulcer, can inhibit gastric acid secretion of gastric acid and histamine as including basic food or coffee, five pentagastrin stimulated gastric acid secretion, also can reduce the nocturnal gastric acid secretion. It was the first anti peptic ulcer drug used in clinic. It is superior to the receptor antagonist in prolonging the ulcer recurrence, but it is less effective than the island receptor antagonist in relieving the pain of peptic ulcer. For stomach and duodenal ulcers, especially for cases with low prostaglandin levels.
It is used for gastric and duodenal ulcer, hemorrhagic gastritis, acute gastric mucosal lesion and other diseases.


Company Profile

 Wuhan Hengwo Scien-Tech Co., Ltd.,is a leading supplier of raw steroids in China.We specialize in producing and seliing various kinds of
Raw steroid powders,semi-finished liquid injectable/oral steroids,polypeptide and natural hormones,Cortiscosteroids,progestational
hormones,etc.With High quality raw materials and advanced clean workshop,as well as strict quality control,our steroid hormones got many good feedback from all over the world.


Technique support is available whenever you have questions in making the steroid powders into finished products or when using.With over 14 years'
experiences exporting steroids worldwide,we have a high customs pass rate,also packages will be free resent to you in case it get seized."Delivery
guarantee,Quality service"is our promisr for you!

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